Discover the 5 Best Places to Live in South America – Affordable & Stunning Destinations (2025)

5 Best Places To Live In South America: Buenos Aires, Argentina

As one of the best places to live in South America, Buenos Aires offers an incredible blend of European charm and Latin American energy, making it a top choice for expats and locals alike.

Rich Cultural Scene

Buenos Aires is a cultural hub with world-class theaters, art galleries, and museums. We can immerse ourselves in tango performances at venues like La Ventana or visit the renowned Teatro Colón, one of the best opera houses globally. Its literary scene is equally impressive, with countless bookstores and cafes paying homage to the city’s creative spirit.

Affordable Cost of Living

Compared to major US cities, Buenos Aires boasts a much lower cost of living. Renting a modern apartment in trendy neighborhoods like Palermo or Recoleta is affordable, and dining out at upscale restaurants won’t break the bank. Groceries, transportation, and healthcare also come at a fraction of the cost back home.

Vibrant Nightlife

The city never sleeps, offering something for night owls of all tastes. From chic bars in Palermo Soho to buzzing clubs in Puerto Madero, Buenos Aires’ nightlife is legendary. We can enjoy live music, dance parties, or casual late-night dinners, as locals often do, well into the early hours.

5 Best Places To Live In South America: Medellín, Colombia

Known as the “City of Eternal Spring”, Medellín has transformed into one of the best places to live in South America. Its vibrant culture, modern amenities, and breathtaking surroundings make it a favorite among locals and expats alike. It’s also a great place to travel around, with cities like Cartagena, Cali, and Bogota.

Perfect Weather Year-Round

Medellín boasts mild temperatures averaging 72°F (22°C) all year, thanks to its location in a lush Andean valley. There’s no need for heavy coats or air conditioning, making life here comfortable and enjoyable every day. We can spend time outdoors exploring parks, gardens, and scenic viewpoints without worrying about extreme weather.

Thriving Expat Community

The city has seen a rising expat population in neighborhoods like El Poblado and Laureles, which are packed with cafes, coworking spaces, and international restaurants. Whether it’s expat meetups, language exchange events, or cultural festivals, there’s always something to help us connect and build a sense of community. English-speaking services are also becoming increasingly accessible, catering to US expats.

Improved Infrastructure and Safety

Once infamous for its troubled past, Medellín has undergone remarkable urban renewal. The Metro system is clean, reliable, and affordable, complemented by unique transportation options like cable cars and escalators that connect hillside neighborhoods. Safety has significantly improved, with more police presence and the city actively investing in public spaces and community programs. Today, Medellín stands as a shining example of innovation and resilience in South America.

5 Best Places To Live In South America: Santiago, Chile

Santiago, Chile, is one of the best places to live in South America, offering a perfect blend of urban sophistication and natural beauty. This vibrant capital city attracts both expats and locals with its modern infrastructure and picturesque surroundings.

Modern Amenities and Facilities

Santiago boasts state-of-the-art amenities that rival those of any North American city. From world-class hospitals to high-quality international schools, it’s an ideal choice for families. The city’s efficient public transportation system, including the well-connected Metro, makes commuting easy and affordable. Shopping malls like Costanera Center and Parque Arauco provide access to global brands, while numerous upscale restaurants and cafes cater to foodies.

Access to Stunning Natural Landscapes

Nestled in a valley with the Andes Mountains as a backdrop, Santiago offers breathtaking scenery just a short drive away. We can go skiing in resorts like Valle Nevado during winter or wine tasting in the Maipo Valley throughout the year. Outdoor enthusiasts will love exploring nearby hiking trails in Cajón del Maipo or taking day trips to the Pacific coast to visit cities like Valparaíso and Viña del Mar.

Strong Economy and Job Opportunities

Chile’s robust economy makes Santiago a hub for career opportunities in South America. The city is home to major financial institutions, multinational corporations, and tech startups, providing options for professionals in various fields. With numerous coworking spaces and startup incubators, Santiago is also building a reputation as a center for innovation. The cost of living is reasonable compared to US cities like New York or San Francisco, making it easier to maintain a high quality of life.

5 Best Places To Live In South America: Montevideo, Uruguay

Montevideo, the capital of Uruguay, is an inviting city with a unique charm that stands out as one of the best places to live in South America. Known for its rich history, safety, and natural coastal beauty, it offers a balanced and fulfilling lifestyle.

Safe and Peaceful Environment

Montevideo boasts a reputation as one of the safest capitals in South America. Its low crime rates, compared to other cities in the region, make it an excellent choice for families and retirees seeking a peaceful place to live. Neighborhoods like Pocitos and Carrasco are particularly secure and popular with expats. The city’s infrastructure supports a sense of safety with clean, well-maintained streets and a strong police presence.

High Quality of Life

Montevideo consistently ranks high in quality of life indices among South American cities. Its healthcare system is modern and accessible, offering both public and private options that cater to residents. The city’s urban design incorporates plenty of green spaces, including Parque Rodó and Prado Park, which provide opportunities to relax and enjoy outdoor activities. Additionally, Uruguay’s stable economy and strong social safety net add to the overall sense of well-being here.

Beautiful Beaches and Relaxed Lifestyle

Montevideo’s picturesque coastline, known as the Rambla, stretches for over 13 miles and is perfect for leisurely strolls or biking while enjoying ocean views. Beaches like Pocitos and Playa Ramirez are integral to the city’s laid-back culture, where locals and visitors gather to sunbathe, swim, or enjoy a traditional mate tea. The pace of life here is slower, offering a perfect contrast to the hustle of larger metropolitan areas. Combined with the city’s cultural scene, including tango bars and theaters, Montevideo provides a relaxed yet rich lifestyle.

5 Best Places To Live In South America: Quito, Ecuador

Quito, Ecuador, is one of the best places to live in South America, offering a mix of affordability, natural wonders, and historical elegance. Nestled high in the Andes, this vibrant capital city is perfect for those seeking a unique blend of culture and adventure.

Affordable and Diverse Housing Options

Quito provides a range of affordable housing options, from modern apartments in La Carolina to charming colonial-style homes in Quito’s historic center. Rent prices in this city are significantly lower than in most US cities, with furnished two-bedroom apartments available for as little as $500-$800 per month. For expats, neighborhoods like Cumbayá and González Suárez offer upscale living with access to international schools, gourmet dining, and lush park spaces.

Proximity to Nature and Adventure

Quito’s location sets it apart with easy access to some of Ecuador’s most stunning attractions. Just a short drive away, you can find yourself hiking on majestic volcanoes like Cotopaxi or exploring the Mindo Cloud Forest. For day trips, the famous Middle of the World Monument lets you straddle the equator. Adventure lovers will also appreciate Quito’s proximity to the Amazon Basin and the Galápagos Islands, making it a gateway for extraordinary excursions.

Historic and Artistic Charm

As a UNESCO World Heritage Site, Quito boasts one of the best-preserved historic centers in South America. Walking through streets lined with colonial architecture, you’ll discover landmarks like the stunning Basílica del Voto Nacional and the vibrant Plaza de la Independencia. Quito is a cultural hotspot too, with art galleries, museums, and events that celebrate both traditional Andean heritage and contemporary art scenes. La Ronda neighborhood stands out for its lively artisan workshops, cozy cafes, and street performances.

5 Best Places To Live In South America

South America offers an incredible variety of places to call home, each with its own unique appeal. From bustling cities filled with culture to serene coastal retreats, the region provides something for everyone. Its affordability, welcoming communities, and diverse landscapes make it a standout destination for those seeking a new lifestyle.